Clinical Trial Assessing Two Protocols to Withdraw Non-invasive Ventilation in Hypercapnic Respiratory Failure

A Randomized Controlled Trial Comparing Two Protocols to Withdraw Non-invasive Ventilation (NIV) After an Episode of Hypercapnic Respiratory Failure

The purpose of the study is to determine the optimal method to withdraw non-invasive ventilation after an episode of hypercapnic respiratory failure.

Inclusion Criteria:

• Acute hypercapnic respiratory failure.
• Use of NIV to treat respiratory failure.
• Persistence of hypercapnia after discontinuation of NIV

Exclusion Criteria:

• Home NIV
• Facial or cranial trauma or surgery,
• Recent gastric or esophageal surgery,
• Active upper gastrointestinal bleeding,
• Excessive amount of respiratory secretions,
• Tracheostomy
• Lack of cooperation