Olopatadine Eye Drops and Allergy Skin Testing

Effect of Olopatadine Hydrochloride 0.2% Ophthalmic Solution on Epicutaneous Skin Prick Testing With Histamine and Saline

Use of olopatadine ophthalmic solution (eye drops) will decrease allergy skin test reactivity.

Inclusion Criteria:

• Adults aged 18 to 75 years
• Healthy volunteers (no major illnesses or active symptoms)

Exclusion Criteria:

• Known allergy or hypersensitivity to the drugs or components
• Pregnant or nursing women
• Women wishing to become pregnant during the study's duration
• Use of topical or oral medications with antihistaminic activity for 14 days proceeding randomization
• Dermatographism as evidenced on skin testing on visit 1
• Chronic urticaria active within the past 6 months
• Severe hypertension
• Psychiatric diagnoses which could potentially affect medication compliance, such as schizophrenia or delusional disorders, as determined by the investigator obtaining informed consent and based on the subject's past medical history
• Inability to provide informed consent