Adiponectin and Insulin Resistance in Diabetic Nephropathy

Adiponectin is Positively Associated With Insulin Resistance in Subjects With Type 2 Diabetic Nephropathy and Effects by Angiotensin Type 1 Receptor Blocker Losartan

Plasma adiponectin concentration is inversely associated with renal function. There is little literature on adiponectin levels and regulation by antihypertensive medication with an angiotensin II-receptor blocker (ARB), especially in subjects with type 2 diabetes in different stage of chronic kidney disease (CKD).

Inclusion Criteria:

• Type 2 diabetic nephropathy
• CKD at stage 1~4

Exclusion Criteria:

• Type 1 diabetes or nondiabetic renal disease
• An elevated plasma K level.