The proposed study is a pilot study and a first step towards developing an optimized HPV vaccination strategy for girls who have CKD, or are on dialysis or have a kidney transplant.

Inclusion Criteria:

• 9-18-year-old girls who have CKD stages 3 or 4 (Glomerular filtration rates 15-59 mL/min/1.73m2).
• 9-18-year-old girls who are on dialysis.
• 9-18-year-old girls who have had a functioning kidney transplant for longer than 6 months and are on the same immunosuppression regimen.
• Healthy 9-18-year-old girls

Exclusion Criteria:

• Pregnancy, fever, allergy to any vaccine component, any immune disorder and any blood product received in the previous 6 months.

Girls age 9-18 who are healthy, have chronic kidney disease stage 3 or 4, are on dialysis, or have had a functioning kidney transplant for longer than 6 months and are on the same immunosuppression regimen.