14729-D9831C00002- 1 Month Biopsy Study

A Double-blind, Placebo-controlled, Randomised, Parallel Group Phase IIa Study to Evaluate the Histological Changes, Cellularity, Clinical Efficacy and Safety of AZD1981 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

The purpose of this study is to study histological changes, cellularity, clinical efficacy and safety of AZD1981 in patients with Chronic Obstructive Pulmonary Disease

Inclusion Criteria:

• Men or women 40 years or above
• FEV1 between 40 and 80% of predicted normal value post-bronchodilator
• Clinical diagnosis of COPD

Exclusion Criteria:

• Other clinically relevant disease or disorders
• Exacerbation of COPD within 30 days