Treatment for Word Retrieval Impairments in Aphasia | NCT00764400

Studies
Treatment for Word Retrieval Impairments in Aphasia

NCT00764400

Sponsor

Old Dominion University

Status

Completed

Last Update Posted

Apr 6, 2018Actual

Enrollment

24Actual

Phase

Not Applicable

Conditions

Stroke

Interventions

Word Retrieval Treatments for Aphasia

Countries

United States

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

ID	Type	Description	Link
3R15DC009690	U.S. NIH Grant/Contract		View source

Status Module

Record Verification Date

Apr 2018

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Aug 2008

Primary Completion Date

Jun 2013Actual

Completion Date

Jul 2013Actual

First Submitted Date

Sep 30, 2008

First Submission Date that Met QC Criteria

Sep 30, 2008

First Posted Date

Oct 2, 2008Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Apr 4, 2018

Last Update Posted Date

Apr 6, 2018Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Dr. Anastasia Raymer, Professor of Communications Disorders & Special Education, Old Dominion UniversityPrincipal Investigator

Lead Sponsor

Old Dominion UniversityOTHER

Collaborators

Name	Class
National Institute on Deafness and Other Communication Disorders (NIDCD)	NIH

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Not provided

Is FDA Regulated Device

Not provided

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Detailed Description

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

24Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Errorless Naming Treatment	Experimental		Behavioral: Word Retrieval Treatments for Aphasia
Verbal+Gestural Facilitation	Experimental		Behavioral: Word Retrieval Treatments for Aphasia

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Word Retrieval Treatments for Aphasia	Behavioral	Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Daily Probe Picture Naming		daily probes from three times per week for up to 3 months and one month posttreatment

Secondary Outcomes

Measure	Description	Time Frame
Western Aphasia Battery		pre-treatment and at treatment completion
Boston Naming Test		pretreatment and at treatment completion
Discourse Sample

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

left hemisphere stroke >4 months earlier
aphasia with word retrieval impairments
>21 years of age right handed
speaker of English as the preferred language
>6 grade education

Exclusion Criteria:

history of developmental learning difficulties
history of prior neurological illnesses
chronic medical illnesses that restrict participation in speech therapy
alcohol or drug dependence
severe uncorrected impairments of vision or hearing

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

21 Years

Maximum Age

90 Years

Standard Ages

AdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Anastasia M Raymer, PhD	Old Dominion University	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Old Dominion University Speech and Hearing Clinic		Norfolk	Virginia	23529	United States

Condition Browse Module

MeSH Terms

ID	Term
D020521	Stroke
D001037	Aphasia
D000849	Anomia
D003147	Communication Disorders

Ancestor Terms

ID	Term
D002561	Cerebrovascular Disorders
D001927	Brain Diseases
D002493	Central Nervous System Diseases
D009422	Nervous System Diseases

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