An fMRI Study Of Brain Response In Patients With Fibromyalgia

A Double-Blind, Placebo-Controlled Cross-Over Study In Fibromyalgia Subjects To Examine Effects Of Pregabalin On Brain Response To Mechanical Pain As Assessed By Functional Magnetic Resonance Imaging, Proton Magnetic Resonance Spectroscopy And Subjective Ratings

The purpose of this study is to explore how pregabalin works in patients with fibromyalgia by evaluating brain imaging signals. To find out whether fMRI (functional magnetic resonance imaging) is an efficient way to show whether new pain medications are effective in treating fibromyalgia.

Methodology study

Inclusion Criteria:

• Women must have pain due to fibromyalgia
• Fibromyalgia must have been diagnosed at least 6 months prior to be eligible for this study

Exclusion Criteria:

• Patients with severe depression or other serious illness, who are left-handed, or who are pregnant or nursing are not eligible for this study.