The Use of Low Molecular Weight Heparin in Hemodiafiltration

The Use of Low Molecular Weight Heparin in Hemodiafiltration

Low molecular weight heparin (LMWH) is injected in the dialysis circuit at the start of the session. In the present study we compare 3 different methods of injection of LMWH: parameters of dialysis efficiency and clotting are measured. The study lasts 3 sessions for each patient.

Inclusion Criteria:

• chronic kidney disease stade V treated with hemodiafiltration
• age >18 year
• Hematocrit > 30%

Exclusion Criteria:

• treatment with vitamin K antagonists
• treatment with other anti-coagulants or heparin besides the heparin used during dialysis
• active bleeding, infection or malignancy
• heparin associated allergy
• hepatic failure
• trombocytopenia < 120.000/µl