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| Name | Class |
|---|---|
| Michael J. Fox Foundation for Parkinson's Research | OTHER |
| ZonMw: The Netherlands Organisation for Health Research and Development | OTHER |
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Patients with Parkinson's disease (PD) are heavily inclined towards a sedentary lifestyle. This is caused by a combination of physical impairments and cognitive dysfunction. However, regular physical activity in PD is highly desirable, for two reasons. First, physical activity has positive generic effects in preventing complications such as cardiovascular diseases, type II diabetes mellitus, osteoporosis and certain cases of cancer. Secondly, physical activity has additional disease-specific merits in PD such as depression, sleep disturbances and constipation. These effects lead to raised quality of life. Furthermore, animal studies suggest that physical activity could slow down disease progression.
Simply informing patients about the importance of physical activity is not enough to initiate and maintain an adequate level of physical activity. We propose to develop a physical activity promoting program for sedentary patients with PD in order to raise their level of daily physical activity.
Objective: The first aim of the study is to investigate whether a physical activity promotion program will result in an increase in physical activity in sedentary patients with PD.
The second aim is to demonstrate an increase in physical fitness and quality of life.
no extensive description
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Experimental | Physical Therapy aimed to promote the level of physical activity |
|
| B | Active Comparator | Physical Therapy aimed to move safely |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical therapy aimed to move safely | Other | Physical Therapy according to the Dutch guidelines for Physical Therapy in Parkinson's Disease solely focused on safety of movement. Duration program: 2 years Maximum number of sessions: 35 per year Duration sessions: 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Level of Physical Activity based on the LAPAQ questionnaire | Average of 6, 12, 18 and 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| One week diary of physical activity | Average of 6, 12, 18 and 24 months | |
| Level of Physical Activity based on an activity monitor | continuous during 24 months | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marten Munneke, Dr. | UMC st Radboud | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tergooiziekenhuizen | Hilversum | Postbus 10016 | 1201 DA | Netherlands | ||
| Jeroen Bosch Ziekenhuis |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23457213 | Derived | van Nimwegen M, Speelman AD, Overeem S, van de Warrenburg BP, Smulders K, Dontje ML, Borm GF, Backx FJ, Bloem BR, Munneke M; ParkFit Study Group. Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial. BMJ. 2013 Mar 1;346:f576. doi: 10.1136/bmj.f576. | |
| 20723221 | Derived |
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| Physical Therapy aimed to improve Physical Activity | Other | Physical Therapy according to the Dutch guidelines for Physical Therapy in Parkinson's Disease combined with a coaching program aimed to promote the level of physical activity Duration program: 2 years Maximum number of sessions: 35 per year Duration of sessions: 30 minutes |
|
| Physical Fitness (Six Minute Walk Test & Astrand bicycle test) |
| 12 and 24 months |
| Quality of Life (PDQ-39) | 6, 12, 18 and 24 months |
| Mood and Depression (HADS) | 6, 12, 18 and 24 months |
| Cognition (CANTAB) | 12 and 24 months |
| disease severity ( Nine Hole Peg test, UPDRS) | 12 and 24 months |
| Safety(Falls) | monthly |
| Mobility (Timed up and go test) | 12 and 24 months |
| Fatigue (FSS) | 6, 12, 18 and 24 months |
| Medication (questionnaire) | 6, 12, 18 and 24 months |
| Medical Costs (questionnaire) | 6, 12, 18 and 24 months |
| Quality of Sleep (SCOPA-sleep) | 6, 12, 18 and 24 months |
| 's-Hertogenbosch |
| Postbus 1101 |
| 5200 BD |
| Netherlands |
| Catharina ziekenhuis | Eindhoven | Postbus 1350 | 5602 ZA | Netherlands |
| Vie Curie Medisch Centrum | Venlo | Postbus 1926 | 5900 BX | Netherlands |
| Hagaziekhuis | The Hague | Postbus 40551 | 2504 LN | Netherlands |
| Medisch Centrum Haaglanden | The Hague | Postbus 432 | 2501 CK | Netherlands |
| Medisch Centrum alkmaar | Alkmaar | Postbus 50 | 1800 AM | Netherlands |
| Maaslandziekenhuis | Sittard | Postbus 5500 | 6130 MB | Netherlands |
| Tergooiziekenhuizen | Blaricum | Postbus 900 | 1250 CA | Netherlands |
| Gelreziekenhuizen | Apeldoorn | Postbus 9014 | 7300 DS | Netherlands |
| Amphia Ziekenhuis | Breda | Postbus 90157 | 4800 RL | Netherlands |
| De Gelreziekenhuizen | Zutphen | Postbus 9020 | 7200 GZ | Netherlands |
| Ziekenhuis Gelderse Vallei | Ede | Postbus 9025 | 6710 HN | Netherlands |
| Elkerliek ziekenhuis | Helmond | Postbus 98 | 5700 AB | Netherlands |
| Reinier de Graaf Groep | Delft | Netherlands |
| Deventer Ziekenhuis | Deventer | Netherlands |
| Slingeland Ziekenhuis | Doetinchem | Netherlands |
| St. Anna Ziekenhuis | Geldrop | Netherlands |
| Groene Hart Ziekenhuis | Gouda | Netherlands |
| Kennemer Gasthuis | Haarlem | Netherlands |
| Atrium Medisch Centrum | Heerlen | Netherlands |
| Westfriesgasthuis | Hoorn | Netherlands |
| Academisch Ziekenhuis Maastricht | Maastricht | Netherlands |
| Ziekenhuis Bernhoven | Oss | Netherlands |
| Laurentius Ziekenhuis | Roermond | Netherlands |
| Franciscus Ziekenhuis | Roosendaal | Netherlands |
| Erasmus Medisch Centrum | Rotterdam | Netherlands |
| Maasstad Ziekenhuis | Rotterdam | Netherlands |
| Sint Franciscus Gasthuis | Rotterdam | Netherlands |
| Vlietland Ziekenhuis | Schiedam | Netherlands |
| Orbis Medisch Centrum | Sittard | Netherlands |
| 't Lange Land Ziekenhuis | Zoetermeer | Netherlands |
| van Nimwegen M, Speelman AD, Smulders K, Overeem S, Borm GF, Backx FJ, Bloem BR, Munneke M; ParkFit Study Group. Design and baseline characteristics of the ParkFit study, a randomized controlled trial evaluating the effectiveness of a multifaceted behavioral program to increase physical activity in Parkinson patients. BMC Neurol. 2010 Aug 19;10:70. doi: 10.1186/1471-2377-10-70. |
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D001519 | Behavior |
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