Pap Smear Research Study

Evaluation of the Role of Human Papillomavirus Testing and p16 Expression in the Management of Patients Undergoing Cervical Cancer Screening

The principal hypothesis of this study is that HPV testing and/or p16 testing, either alone or in combination or associated with a Pap smear, will demonstrate greater specificity for clinically significant precancerous disease than will a Pap smear alone and that these tests will be of comparable or superior sensitivity than the Pap smear.

Inclusion Criteria:

• 18 years and older
• Ability to speak and clearly understand English
• Female patients

Exclusion Criteria:

• No previous history of Cervical Cancer Treatment(LEEP,Laser,Cone etc.)
• Women who have had Pap smears within the previous 10 months
• Women under the age of 18.
• Women who are pregnant.
• Inability to give informed consent in English