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| Name | Class |
|---|---|
| German Research Foundation | OTHER |
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Airway dendritic cells control pulmonary immune responses to inhaled particles. It is the aim of the present study to investigate the acute effects of smoking on the number and surface molecule expression of human airway dendritic cells.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Participants smoke 8 cigarettes in 4 hours. |
|
| 2 | Sham Comparator | Participants are not allowed to smoke for 4 hours. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Smoking | Behavioral | Active Comparator: Participants smoke 8 cigarettes in 4 hours. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Total number of dendritic cells in bronchoalveolar lavage fluid | June - September 2008 |
| Measure | Description | Time Frame |
|---|---|---|
| Surface molecule expression on dendritic cells in bronchoalveolar lavage fluid | June - September 2008 |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Johann C. Virchow, Professor, MD, FRCP, FCCP | University of Rostock | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Rostock | Rostock | 18057 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18203971 | Background | Bratke K, Klug M, Bier A, Julius P, Kuepper M, Virchow JC, Lommatzsch M. Function-associated surface molecules on airway dendritic cells in cigarette smokers. Am J Respir Cell Mol Biol. 2008 Jun;38(6):655-60. doi: 10.1165/rcmb.2007-0400OC. Epub 2008 Jan 18. |
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| ID | Term |
|---|---|
| D014029 | Tobacco Use Disorder |
| D000073865 | Cigarette Smoking |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
| D000073869 | Tobacco Smoking |
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| ID | Term |
|---|---|
| D000074602 | Smoking Devices |
| ID | Term |
|---|---|
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
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| Smoking |
| Behavioral |
Sham Comparator: Participants are not allowed to smoke for 4 hours. |
|
| D012907 | Smoking |
| D001519 | Behavior |
| D064424 | Tobacco Use |