Study cancelled.

The main objective of the trial is to determine whether the current topical formulation of GTX 2/3 reduces the wrinkling of the skin (crow's feet) after a single application

Other evaluation criteria include: safety assessment and local tolerance, depth of facial wrinkles (video microscopy imaging).

This is a single volunteer group study. Each volunteer will be her own control. A volunteer will receive the active product containing cream on one side of her face and will receive the placebo cream on the other side.

Inclusion Criteria:

• Women with no bearing-child potential or with adequate birth control method.
• Volunteers between 30 to 60 years of age.
• Subjects with bilateral crow's feet wrinkles.
• Regular user of cosmetic products, willing and able to comply with the study objectives.
• Signed informed consent.

Exclusion Criteria:

• Any medical condition or any use of a medication that could modify the study results (e.g.: NSAIDs, immunosuppressant drugs, insulin...).
• Any other significant medical condition (e.g.: diabetes mellitus, heart disease, liver disease...).
• Any other condition that in the investigator's opinion could not be appropriate with the participation in this trial.
• Any health condition that could affect the evaluation of study parameters.
• Acute or chronic skin disease.
• History of allergic reaction to cosmetic compounds.
• Pregnancy, planned pregnancy or breast-feeding.
• Allergy to shellfish, fish or sea product (seaweed).
• Known or suspected hypersensitivity to any of the study product compounds.
• Participation in another clinical trial within 30 days previous to enrolment.
• Known or suspected alcohol or drug abuse.