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couldn't recruit patients
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| Name | Class |
|---|---|
| Rambam Health Care Campus | OTHER |
| Soroka University Medical Center | OTHER |
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Eye burns may cause a severe permanent damage. One kind of treatment is the use of vitamin C (Ascorbic acid). This study will compare between subconjunctival topical and/or systemic route of administration and topical and/or systemic administration.
In order to prevent permanent and severe damage to the eye after eye burn early treatment is mandatory. It is well known and published that the use of Vitamin c may contribute to the healing process of such burns, including burns from chemicals or heat. We believe that the route pf administration of the medicine is as important as the kind of medicine and that subconjunctival injection will have better effect and will influence in a favorable manner on the the end result as well as on the time of the healing.
In order to be able to compare between cases we made a new definition of the severity of the burn according to the extension of the damage on the cornea, conjunctiva and limbus, and according to the severity and depth of the ischemia.
In 3 medical centers 3 protocols of treatment and followup will be compared while only in Baruch Pade Medical Center the main route of administration will be subconjunctival on top of the topical treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | Baruch Pade Medical Center |
|
| 2 | Active Comparator | Rambam Medical Center |
|
| 3 | Active Comparator | Soroka Medical Center |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| vitamin c | Dietary Supplement | Subconjunctival daily or bid |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| EXTENSION OF FLORSCEIN PAINT ON THE CORNEA AND CONJUNCTIVA | BID |
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Inclusion Criteria:
Exclusion Criteria:other disease
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| Name | Affiliation | Role |
|---|---|---|
| naftali modi, MD | Baruch Pade medical center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Movshovitz Ina | Afula | Israel | ||||
| Naftali Modi |
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| ID | Term |
|---|---|
| D002056 | Burns |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D001205 | Ascorbic Acid |
| D014785 | Vision, Ocular |
| ID | Term |
|---|---|
| D013400 | Sugar Acids |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
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| vitamin c | Dietary Supplement | topical and systemic |
|
|
| vitamin c | Dietary Supplement | topical systemic |
|
|
| Tiberias |
| Israel |
| D006880 |
| Hydroxy Acids |
| D002241 | Carbohydrates |
| D055537 | Light Signal Transduction |
| D015398 | Signal Transduction |
| D001669 | Biochemical Phenomena |
| D055598 | Chemical Phenomena |
| D002468 | Cell Physiological Phenomena |
| D012677 | Sensation |
| D009424 | Nervous System Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D009799 | Ocular Physiological Phenomena |