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Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.
The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.
The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training
We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.
The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period
The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High frequency training | Experimental | 24 interval exercises performed 8 times per week |
|
| Normal frequency training | Experimental | 24 interval exercises performed 3 times per week |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High frequency training | Behavioral | 24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oxygen uptake | Before and after the training-, detraining- and retraining-phase |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac function and skeletal muscle enzyme activity | After training, detraining and retraining |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Øivind Rognmo, PhD | Norwegian University of Science and Technology | Principal Investigator |
| Ulrik Wisløff, Professor | National Taiwan Normal University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Norwegian University of Science and Technology | Trondheim | 7020 | Norway | |||
| NTNU |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24516645 | Result | Hatle H, Stobakk PK, Molmen HE, Bronstad E, Tjonna AE, Steinshamn S, Skogvoll E, Wisloff U, Ingul CB, Rognmo O. Effect of 24 sessions of high-intensity aerobic interval training carried out at either high or moderate frequency, a randomized trial. PLoS One. 2014 Feb 7;9(2):e88375. doi: 10.1371/journal.pone.0088375. eCollection 2014. |
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| normal frequence training | Behavioral | 24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining |
|
| Trondheim |
| 7489 |
| Norway |