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Dexamethasone is a safe and cheap abortive therapy for migraine headache. The effect of it is never evaluate and not correlate with the effect of popular anti migraine medication such as dihydroergotamine. The investigators proposal is to compare its effect with dihydroergotamine.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental |
| |
| 2 | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| dexamethazone | Drug | injection form, 8 miligram, injected once |
|
| Measure | Description | Time Frame |
|---|---|---|
| to evaluate the efficacy of dexamethazone in abortive therapy of migraine attack and prevent of recurrence |
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Inclusion Criteria:
Migraine attack according to international headache society criteria
Migraine without aura; at least 5 attack with mean duration of 4 to 72 hours and 2 of following:
Unilateral
Pulsatile
Severe enough to impair daily activity
Aggravate with walking and climbing, also 1 of following:
Migraine with aura; at least 2 attacks with 3 of following:
Exclusion Criteria:
Hypertension
Ischemic heart disease
Basilar migraine with sign and symptoms such as:
Peripheral vascular disease
Sepsis
Age more than 40 and less than 15 year old
Pregnancy
Use of triptans and ergots derivatives in past 24 hours
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peyman Petramfar | Shiraz | Fars | Iran |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| C480824 | 21-benzyloxy-9alpha-fluoro-16alpha-methylpregna-1,4-dien-11beta,17alpha-diol-3,20-dione |
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| D009422 | Nervous System Diseases |