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| ID | Type | Description | Link |
|---|---|---|---|
| P30CA043703 | U.S. NIH Grant/Contract | View source | |
| CASE1508 | Other Identifier | Case Comprehensive Cancer Center | |
| CASE-1508-CC483 |
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Low interest
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
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RATIONALE: Diagnostic procedures, such as optical coherence tomography, may help find and diagnose lung cancer or precancerous cells.
PURPOSE: This phase I trial is studying how well optical coherence tomography of the airway works in detecting abnormal cells in patients undergoing surgery for lung cancer or lung disease.
OBJECTIVES:
OUTLINE: Bronchoscopic imaging and optical coherence tomography are performed on lung tissue samples collected during surgery. All imaged areas are marked. The marked areas are then excised and fixed in formalin for histopathologic analysis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bronchoscopic and lung imaging studies | Procedure | Bronchoscopic imaging and optical coherence tomography are performed on lung tissue samples collected during surgery. | ||
| diagnostic bronchoscopy | Procedure | Bronchoscopic imaging and optical coherence tomography are performed on lung tissue samples collected during surgery. | ||
| histopathologic examination | Procedure | All imaged areas are marked. The marked areas are then excised and fixed in formalin for histopathologic analysis. | ||
| optical coherence tomography | Procedure | Bronchoscopic imaging and optical coherence tomography are performed on lung tissue samples collected during surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation of optical coherence tomography images of the airway with airway histology | This study will involve discarded tissue from 10 subjects with pathology specimens over one year. |
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DISEASE CHARACTERISTICS:
PATIENT CHARACTERISTICS:
PRIOR CONCURRENT THERAPY:
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primary care clinic
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| Name | Affiliation | Role |
|---|---|---|
| Rana Hejal, MD | Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Cleveland | Ohio | 44106-5065 | United States |
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| Label | URL |
|---|---|
| Clinical trial summary from the National Cancer Institute's PDQ® database | View source |
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Fresh Bronchi from 10 subjects undergoing pneumonectomy or lobectomy for malignant and benign processes will be obtained from the UHCMC Pathology Department as discarded tissue from fresh specimens
| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| D000086002 | Mesothelioma, Malignant |
| D009362 | Neoplasm Metastasis |
| D009369 | Neoplasms |
| D011230 | Precancerous Conditions |
| D002289 | Carcinoma, Non-Small-Cell Lung |
| D055752 | Small Cell Lung Carcinoma |
| C535297 | Recurrent respiratory papillomatosis |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D008654 | Mesothelioma |
| D000236 | Adenoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D018301 | Neoplasms, Mesothelial |
| D010997 | Pleural Neoplasms |
| D009385 | Neoplastic Processes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
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| ID | Term |
|---|---|
| D041623 | Tomography, Optical Coherence |
| ID | Term |
|---|---|
| D041622 | Tomography, Optical |
| D061848 | Optical Imaging |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D014054 | Tomography |
| D008919 | Investigative Techniques |
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