The principal aim of this project is to determine the time course of development of contact lens and contact lens case contamination during daily wear of silicone hydrogel lenses. The secondary aim of the study is to determine whether the time course of development of contact lens and contact lens case contamination varies between two different contact lens care systems.

Inclusion Criteria:

• Distance contact lens prescription between +8.00 and -10.00D.
• Cylindrical component of refractive error no greater than 1.25D in either eye.
• Vision correctable to 6/12 (0.30 logMAR) or better in each eye.
• Healthy normal eyes without anterior segment infection, inflammation or abnormality, or significant slitlamp findings.

Exclusion Criteria:

• Concurrent ocular medication
• Eye injury or surgery within twelve weeks immediately prior to enrolment.
• Current ocular irritation that would preclude contact lens fitting.
• Evidence of systemic or ocular abnormality, infection or disease likely to affect successful wear of contact lenses or use of their accessory solutions.
• Pregnant, lactating or planning a pregnancy.