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| Name | Class |
|---|---|
| Bangor University | OTHER |
| Science in Sport | UNKNOWN |
| Plans Branch of Headquarters Army Recruiting and Training Division | UNKNOWN |
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During a multi-week expedition to the Himalaya, we aim to investigate i) whether dietary supplementation with carbohydrate drinks and gels can improve physical performance; and ii) the underlying mechanisms for any observed changes in performance.
We hypothesise that i) carbohydrate supplementation will improve physical performance; and ii) the underlying mechanism of this improvement in performance will include maintenance of body glycogen (sugar) stores, prevention of dehydration and decrease in the incidence of acute mountain sickness.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | Carbohydrate supplements (drinks and gels) |
|
| 2 | Placebo Comparator | Primarily Aspartame plus natural flavourings. Powder dissolved in water to provide non-distinguishable placebo drink. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Carbohydrate energy drink | Dietary Supplement | Complex carbohydrates including maltodextrin (97%) dissolved in water to make a a 10% solution, or dissolved in 25mL gels. Ad libitum. Twenty two days. |
| Measure | Description | Time Frame |
|---|---|---|
| Performance (time to complete a physical performance task) | Mid study |
| Measure | Description | Time Frame |
|---|---|---|
| Body composition | Pre, mid and post study | |
| Hydration status | Pre, mid and post study | |
| Body glucose stores |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jamie H Macdonald, PhD | Bangor University | Principal Investigator |
| Samuel J Oliver, PhD | Bangor University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical Expeditions Ltd | Pinfold, Hyssington, Montgomery | Powys | SY15 6AY | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19793859 | Derived | Macdonald JH, Oliver SJ, Hillyer K, Sanders S, Smith Z, Williams C, Yates D, Ginnever H, Scanlon E, Roberts E, Murphy D, Lawley J, Chichester E. Body composition at high altitude: a randomized placebo-controlled trial of dietary carbohydrate supplementation. Am J Clin Nutr. 2009 Nov;90(5):1193-202. doi: 10.3945/ajcn.2009.28075. Epub 2009 Sep 30. |
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| ID | Term |
|---|---|
| D000860 | Hypoxia |
| D000532 | Altitude Sickness |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |
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| ID | Term |
|---|---|
| D001218 | Aspartame |
| ID | Term |
|---|---|
| D004151 | Dipeptides |
| D009842 | Oligopeptides |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
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|
| Aspartame | Dietary Supplement | Aspartame dissolved in water, ad libitum, 22 days. |
|
|
| Pre, mid and post study |
| Oxygen delivery | Pre, mid and post study |
| Acute mountain sickness | Every day |
| Spontaneous physical activity level | Pre, mid and post study |
| Rating of perceived exertion during a stepping task | Pre, mid and post study |
| D012140 | Respiratory Tract Diseases |