A RCT was conducted to elucidate whether the treatment outcome of HCC could be improved by RFA associated with postoperative TACE.

A randomized study was conducted to elucidate whether the outcome of hepatocellular carcinoma could be improved by radiofrequency ablation associated with postoperative transhepatic arterial chemoembolization.

Inclusion Criteria:

• patients with hepatocellular,confirmed by pathological examination
• patients with a live function test showed Child A or B
• Indocyanine green test showed less than 30％ after 15min,and the patients showed a tolerance of RFA and TACE
• Tumor stage is early period(according to Milan Standard),that is,the diameter of single node should be less than 5cm；the node of tumor should be less than 3 and the diameter less than 3cm.
• without metastasis in lymphnode or other organs
• written consent inform assigned

Exclusion Criteria:

• preoperative examination showed malignant thrombosis in the first class branch of portal vein or hepatic vein or vena cava
• metastatic cancer of liver
• patients with a poor tolerance of RFA and TACE
• patients received other therapies.