Oral Glyceryl Triacetate (GTA) in Newborns With Canavan

Oral Glyceryl Triacetate (GTA) in Newborns With Canavan

Canavan disease is caused by Aspartoacylase deficiency. There is no treatment for the disease, but there is a food additive that includes acetate . We suggest an early treatment with acetate and a neurologic evaluation, including MRI, after 4 months of treatment. In any case the treatment will be stopped at the age of 22 months, when myelinization is ended.

Inclusion Criteria:

• clinical diagnosis of Canavan disease

Exclusion Criteria:

• Age above 18 months