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| ID | Type | Description | Link |
|---|---|---|---|
| 2007-439 | |||
| U54NS057405 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Medstar Health Research Institute | OTHER |
| Howard University | OTHER |
| George Washington University | OTHER |
| University of Michigan |
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The purpose of this study is to increase treatment of acute stroke with tissue plasminogen activator (tPA) across the District of Columbia. This study, however, will not evaluate tPA as an intervention.
There are a number of well-known barriers to receiving tissue plasminogen activator (tPA) including transit time to hospital, paramedic and provider training, tPA standing orders, and provider guidelines. Among underserved populations, limited stroke knowledge, socioculturally determined attitudes, and beliefs and myths held by community members may serve as additional barriers that hinder these populations from receiving tPA and acute stroke care. Targeted multilevel interventions designed to overcome specific barriers may significantly increase the number of individuals with stroke who are appropriately treated with intravenous tPA (IV tPA) in underserved communities. Identification of the specific components of healthcare interventions that are the most effective is critical to improve delivery of acute stroke therapy.
The goal of this study is to learn more about public knowledge, attitudes, beliefs and perceptions regarding stroke and stroke treatment in order to identify sociocultural and environmental barriers to receiving tPA and acute stroke care in an underserved community. This study will also determine if implementation of a multilevel intervention program can significantly increase the number of people with ischemic stroke who are appropriately treated with IV tPA in a predominantly underserved community.
In the study, researchers will evaluate the different levels of the intervention to determine which efforts are most effective.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Adults living in DC neighborhoods with high proportions of underserved adults. The age of the cohort members will reflect the age of DC residents who suffer most from stroke. |
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| Measure | Description | Time Frame |
|---|---|---|
| The proportion of people with ischemic stroke appropriately treated with IV tPA. | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Qualitative data collected from the community will identify baseline levels of knowledge, attitudes, and perceived and encountered barriers to acute stroke treatment. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
-
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Adult residents of the District of Columbia
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| Name | Affiliation | Role |
|---|---|---|
| Chelsea Kidwell, MD | Georgetown University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Georgetown University, ASPIRE Coordinating Center | Washington D.C. | District of Columbia | 20007 | United States | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24876243 | Derived | Boden-Albala B, Edwards DF, St Clair S, Wing JJ, Fernandez S, Gibbons MC, Hsia AW, Morgenstern LB, Kidwell CS. Methodology for a community-based stroke preparedness intervention: the Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities Study. Stroke. 2014 Jul;45(7):2047-52. doi: 10.1161/STROKEAHA.113.003502. Epub 2014 May 15. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| OTHER |
| University of Wisconsin, Madison | OTHER |
| Johns Hopkins University | OTHER |
| University of Alabama at Birmingham | OTHER |
| MedStar Good Samaritan Hospital | UNKNOWN |
| Union Memorial Hospital | OTHER |
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| Washington Hospital Center |
| Washington D.C. |
| District of Columbia |
| 20010 |
| United States |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | United States |
| Providence Hospital | Washington D.C. | District of Columbia | 20017 | United States |
| United Medical Center (formerly known as Greater Southeast Community Hospital) | Washington D.C. | District of Columbia | 20032 | United States |
| George Washington University Hospital | Washington D.C. | District of Columbia | 20037 | United States |
| Howard University Hospital | Washington D.C. | District of Columbia | 20060 | United States |
| Columbia University Medical Center | New York | New York | 10032 | United States |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |