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| ID | Type | Description | Link |
|---|---|---|---|
| UMCC 0005 | Other Identifier | Univ. of Michigan Comprehensive Cancer Center | |
| P01CA087634 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institutes of Health (NIH) | NIH |
| National Cancer Institute (NCI) | NIH |
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The purpose of this study is to determine how well changes can be determined in malignant masses from ultrasound scans.
To evaluate the proportions of correct diagnosis of response to breast Cancer therapies for localized breast cancer by ultrasound. To develop a model based on patient characteristics, physical exam, and radiologic studies which will predict the possibility that a patient has had a complete pathological response to chemotherapy neoadjuvant therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Subjects | Active Comparator | Ultrasound scan |
|
| Cancer | Active Comparator | 120 women diagnosed by biopsy to have breast cancer will have an ultrasound scan |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound Scan | Procedure | 10 female volunteers with normal breast who will be studied to refine imaging techniques and for comparison with patients. To the degree possible, the volunteer group will be age-matched to patients with symptoms, initially 30 to 70 years of age. |
| Measure | Description | Time Frame |
|---|---|---|
| Volume change on spatially registered (aligned) images tracks path. response better than volume change on unregistered images. | Self explanatory. | 2002-2014 |
| Measure | Description | Time Frame |
|---|---|---|
| Spatially register pre, intra and post treatment ultrasound image volumes of treated tumor. | Visually measure separation between two corresponding points in two ultrasound image volumes after registration to verify registration accuracy. | 2002-2014 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paul L. Carson, Ph.D. | University of Michigan | Principal Investigator |
| Paul Carson, PhD | University of Michigan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | United States |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| ID | Term |
|---|---|
| D019220 | High-Energy Shock Waves |
| ID | Term |
|---|---|
| D000069453 | Ultrasonic Waves |
| D013016 | Sound |
| D011840 | Radiation, Nonionizing |
| D011827 | Radiation |
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| Mammography and Ultrasound | Procedure | To determine how well from ultrasound scans, changes in malignant masses can be measured, and to whether the use of a dye visible by ultrasound will be useful in evaluating different therapies for breast cancer. |
|
| D017437 |
| Skin and Connective Tissue Diseases |
| D055585 |
| Physical Phenomena |