Maraviroc Compassionate Use

Maraviroc Compassionate Use

The objective of this study is to provide Maraviroc on a compassionate use basis to antiretroviral treatment experienced patients infected with CCR5-tropic HIV-1 with urgent unmet medical needs and who, in the opinion of the physician, require Maraviroc to form a viable regimen.

This study was cancelled prior to enrollment.

Inclusion Criteria:

• Patients at least 16 years old with prior extensive treatment experience with limited further options in need of maraviroc to constitute an effective HIV-1 treatment regimen.
• Have only CCR5-tropic HIV-1 virus
• CD4+ cell count < 200 cells/mm3

Exclusion Criteria:

• CXCR4- or dual/mixed-tropic HIV-1 virus
• Patients who in the opinion of investigator are unlikely to derive benefit from maraviroc as a result of severity of illness
• Patients who are pregnant or breast feeding an infant or planning to become pregnant.