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Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome. By performing quantitative sensory testing, the specific changes in pain patients will be revealed, thereby aiding in designing future treatment trials. MRI scans of the groin regions in pain patients and control patients will be evaluated by senior MRI specialists assessing potential pathology to the region (Mesh, inflammation, edema, funicle etc.) Assessors will be blinded to clinical status, and surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| pain-free control | Pain-free controls from previous prospective study (KF 01294867), operated >2 years previously | ||
| Pain Patients | Patients with persistent postherniotomy pain lasting >1 year and pain related impaired daily function |
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| Measure | Description | Time Frame |
|---|---|---|
| Sensory function | actual |
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Inclusion Criteria:
Exclusion Criteria:
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persistent posthenriotomy patients
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| Name | Affiliation | Role |
|---|---|---|
| Eske K Aasvang, M.D. | Rigshospitalet, Copenhagen University, Denmark | Study Director |
| Henrik Kehlet, M.D., Ph. D. | Rigshospitalet, Copenhagen University, Denmark | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Danish Pain Research Centre | Aarhus | 8000 | Denmark | |||
| Section for Surgical Pathophysiology |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17976914 | Background | Aasvang EK, Brandsborg B, Christensen B, Jensen TS, Kehlet H. Neurophysiological characterization of postherniotomy pain. Pain. 2008 Jul;137(1):173-181. doi: 10.1016/j.pain.2007.09.026. Epub 2007 Oct 31. | |
| 15531621 | Background | Aasvang E, Kehlet H. Chronic postoperative pain: the case of inguinal herniorrhaphy. Br J Anaesth. 2005 Jul;95(1):69-76. doi: 10.1093/bja/aei019. Epub 2004 Nov 5. No abstract available. |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D009437 | Neuralgia |
| D006552 | Hernia, Inguinal |
| D010146 | Pain |
| D000092122 | Bronchiolitis Obliterans Syndrome |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009461 | Neurologic Manifestations |
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| Copenhagen |
| 2100 |
| Denmark |
| D012816 | Signs and Symptoms |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D046449 | Hernia, Abdominal |
| D006547 | Hernia |
| D020763 | Pathological Conditions, Anatomical |
| D000092124 | Organizing Pneumonia |
| D001989 | Bronchiolitis Obliterans |
| D001988 | Bronchiolitis |
| D001991 | Bronchitis |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D006086 | Graft vs Host Disease |
| D007154 | Immune System Diseases |