Pain Relief of Metoprolol Versus Metoprolol Plus Morphine... | NCT00718406

Studies
Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

NCT00718406

Sponsor

Sahlgrenska University Hospital

Status

Completed

Last Update Posted

Jul 18, 2008Estimated

Enrollment

Not provided

Phase

Phase 4

Conditions

Acute Coronary Syndromes

Interventions

Metoprolol
metoprolol plus morphine

Countries

Sweden

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Aug 2002

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Not provided

Primary Completion Date

Not provided

Completion Date

Not provided

First Submitted Date

Jul 16, 2008

First Submission Date that Met QC Criteria

Jul 16, 2008

First Posted Date

Jul 18, 2008Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jul 16, 2008

Last Update Posted Date

Jul 18, 2008Estimated

Name	Class
AstraZeneca	INDUSTRY

Description Module

Brief Summary

The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Phase 4

Interventional Study Design

No data available

No data is available for this block.

Biospecimen

No data available

No data is available for this block.

Enrollment

Not provided

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
A	Active Comparator	A=metoprolol	Drug: Metoprolol
B	Active Comparator	B=metoprolol plus morphine	Drug: metoprolol plus morphine

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Metoprolol	Drug		A
metoprolol plus morphine

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Acute chest pain
ECG-signs indicating myocardial ischemia

Exclusion Criteria:

Heart rate < 60 beats/min
Systolic blood pressure < 110 mmHg
High degree AV-block
Signs of obstructive pulmonary disease
Signs of pulmonary oedema
Unwillingness
Participation in other studies
Long delay between arrival of ambulance and randomisation

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital		Gothenburg		SE-413 45	Sweden

Condition Browse Module

MeSH Terms

ID	Term
D054058	Acute Coronary Syndrome
D002637	Chest Pain

Ancestor Terms

ID	Term
D017202	Myocardial Ischemia
D006331	Heart Diseases
D002318	Cardiovascular Diseases
D014652	Vascular Diseases

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
D008790	Metoprolol
D009020	Morphine

Ancestor Terms

ID	Term
D050198	Phenoxypropanolamines
D011412	Propanolamines
D000605	Amino Alcohols
D000438	Alcohols

Browse Leaves

Not provided

Browse Branches

Not provided