Nutritional Study in Preterm Infants

Effect of Supplemental Infant Formula on Blood Levels in Preterm Infants

An evaluation of a preterm infant formula containing ingredients similar to those found in breastmilk

Inclusion Criteria:

• Birthweight 500-1800 g
• Less than 33 wks gestational age
• Enteral feeding initiated by 21 days of life
• Asymmetrical small-for-gestational age (SGA) infants and infants with patent ductus arteriosus (PDA) are eligible to participate
• Singleton or twin births only
• Infant is 21 days of age or less at time of randomization

Exclusion Criteria:

• Serious congenital abnormalities that may affect growth and development
• Grade III or IV intraventricular hemorrhage (IVH)
• Maternal incapacity
• History of major surgery
• Extracorporeal membrane oxygenation (ECMO)
• Asphyxia
• Confirmed NEC or positive blood cultures at the time of randomization