An Evaluation of Potential Next-day Residual Effects of Eszopiclone in Healthy Volunteers.

A Randomised, Double-blind, Double-dummy, Placebo-controlled, 3-way Crossover Study to Evaluate Potential Next-day Residual Effects of a Single Evening Dose of 3mg Eszopiclone and 7.5mg Zopiclone in Healthy Adult Subjects.

This study will explore potential next-day residual effects of a single evening dose of 3mg of the hypnotic, eszopiclone, 7.5mg of zopiclone, and placebo, in healthy adult subjects.

INCLUSION CRITERIA:

• Healthy male and female subjects providing written informed consent.

EXCLUSION CRITERIA:

• Significant medical disorders;
• Sleeping difficulties; alcohol and/or substance abuse;
• Recent use of psychotropic medications, or need to use them during study;
• Very high BMI or very low BMI or bodyweight;
• Known hypersensitivity to the study medications or their excipients;
• Unwilling or unable to meet certain lifestyle or dietary restrictions during the study.