The purpose of this study is to determine whether ezetimibe in association with statins is more effective than statins alone on postprandial lipemia in type 2 diabetic patients.

Inclusion Criteria:

• Type 2 diabetes since at least two years
• Stable metabolic control (HbA1c<8.0%) for at least six months on diet or diet+oral hypoglycemic drugs (insulin secretagogues or metformin), not to be changed during the study period.
• BMI<30 kg/m2 and body weight stable during the last six months.
• Both sexes; only post-menopausal women.
• LDL-cholesterol >130 mg/dl, plasma triglycerides <400 mg/dl.
• No use of hypolipidemic drugs in the last three months.

Exclusion Criteria:

• Patient with renal (serum creatinine >1.5 mg/dl) or hepatic (serum transaminases >three times upper normal values) impairment.
• Patients with history of cardiovascular disease.
• Pre-menopausal women.
• Any other acute or chronic degenerative disease.
• Anemia (Hb<12 g/dl).
• Uncontrolled blood pressure.
• Use of any drugs able to interfere with the study medications