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Orbital Venous flow study in patients with Grave's Orbitopathy in different manifestation forms and stages, made with Color Doppler Imaging
Prospective study with Grave's patients in active and fibrotic disease, myogenic and lipogenic forms, with muscle restriction and without muscle restriction and with or without optic compressive neuropathy. Blood flow was studied with Color Doppler Imaging (CDI) in the following orbital vessels:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group control with healthy subjects | Healthy subjects without thyroid disease, ocular disease and previous surgery in the orbit or eye used in the study. | ||
| Graves' Ophthalmopathy - fibrotic phase | Patients that are clinically inactive (CAS equal or lower than 2). This group will be subdivided in the miogenic and lipogenic groups. | ||
| Graves' Ophthalmopathy - active phase | Patients that are clinically active, presenting a CAS of 4 or more points, with or without disthyroid optic neuropathy. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Grave's disease within the orbital service of HCFMUSP at the Ophthalmology Department
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| Name | Affiliation | Role |
|---|---|---|
| Mário LR Monteiro, Professor | Instituto do Coracao | Study Director |
| Joseph E Benabou | Instituto do Coracao | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital das Clínicas da Universidade São Paulo | São Paulo | São Paulo | 05403-000 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21915479 | Derived | Monteiro ML, Moritz RB, Angotti Neto H, Benabou JE. Color Doppler imaging of the superior ophthalmic vein in patients with Graves' orbitopathy before and after treatment of congestive disease. Clinics (Sao Paulo). 2011;66(8):1329-34. doi: 10.1590/s1807-59322011000800004. |
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| ID | Term |
|---|---|
| D006111 | Graves Disease |
| D049970 | Graves Ophthalmopathy |
| ID | Term |
|---|---|
| D005094 | Exophthalmos |
| D009916 | Orbital Diseases |
| D005128 | Eye Diseases |
| D006042 | Goiter |
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| D013959 |
| Thyroid Diseases |
| D004700 | Endocrine System Diseases |
| D006980 | Hyperthyroidism |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D015785 | Eye Diseases, Hereditary |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |