Tobramycin Tear Concentrations

Evaluation of Tobramycin Tear Concentrations of TOBRADEX® Ophthalmic Suspension, Tobramycin 0.3% / Dexamethasone 0.05% Ophthalmic Suspension Versus TOBREX® Ophthalmic Solution in Normal Volunteers

To evaluate the Tobramycin tear concentration values of TOBRADEX® Ophthalmic Suspension, Tobramycin 0.3% / Dexamethasone 0.05% Ophthalmic Suspension versus TOBREX® Ophthalmic Solution in normal volunteers.

Inclusion:

• Visual Acuity (VA) of 0.6 logMAR or better
• Tear meniscus height of ≥ 0.3mm at Visit 1.
• No concomitant topical ocular medications, including artificial tears, during the study period

Exclusion

• ocular hypertension, iritis or uveitis, glaucoma
• ocular surgery, intraocular surgery or ocular laser procedures in either eye within the past six months
• epithelial herpes simplex (dendritic keratitis); Vaccinia, active or recent varicella viral disease of the cornea and/or conjunctiva; ocular Rosacea; Mycobacterial infection of the eye; and / or fungal disease of the eye
• lacrimal duct obstruction, dry eye, ocular allergies.
• contact lens within 7 days of Visit 1.
• ocular medications within 14 days of Visit 1.