Treatment for Acute Spinal Cord Injury

Clinical Study of Treatment for Acute Spinal Cord Injury Using Cultured Bone Marrow Stromal Cells

This clinical trial aims to treat a damaged spinal cord by injecting your own bone marrow stromal cells (autologous bone marrow stromal cells) into cerebrospinal fluid through the lumbar puncture, and assess the safety and efficacy of the procedure.

Inclusion Criteria:

• Spinal cord injury is confirmed with MRI
• Methylprednisolone therapy according to this study can be started within 8 hours after the injury
• Bone marrow stromal cells (BMSCs) incubation can be started within 72 hours after the injury
• Age between 15 and 60
• With the informed consent of obtaining bone marrow and injecting incubated BMSCs.

Exclusion Criteria:

• Complete disruption of spinal cord
• Central spinal cord injury
• Spinal canal stenosis before the injury
• Brain or spinal cord disease before the injury
• Positive serologic test in at least one of the following; HBs antigen, HCV antibody, HIV antibody, or HTLV-1 antibody
• Pregnancy