Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial

A Double-masked, Randomized, Parallel Group, Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial

Comparison of two nasal sprays for the treatment of seasonal allergic rhinitis

Inclusion:

• A history of spring/summer seasonal allergies.
• Positive skin prick test for the currently prevalent allergen of the area.
• Confirmed absence of significant anatomic abnormalities, infection, bleeding, and mucosal ulcerations on nasal examination prior to administration of test article.
• For pre-menopausal females, a negative pregnancy test prior to entry into the study, and, if sexually active, agreement to use adequate birth control methods throughout the study.

Exclusion:

• History of chronic sinusitis.
• Asthma, with the exception of intermittent asthma.
• Smokers.
• Known non-responders to antihistamines.
• Chronic or intermittent use of inhaled, oral, intramuscular, intravenous or dermal potent or super-potent topical corticosteroids.
• Chronic use of long acting antihistamines.
• Upper or lower respiratory infection within 14 days of Visit 1. Diagnosis of acute sinusitis within 30 days of Visit 1.
• Relatives of study site staff or other individuals who had access to the clinical study protocol.
• Participation in any other investigational study within 30 days before entry into this study or concomitantly with this study.