Combined Sono-electro-magnetic Therapy for Treatment of Refractory Chronic Pelvic Pain Syndrome

Combined Sono-electro-magnetic Therapy for Treatment of Refractory Chronic Pelvic Pain Syndrome: A Prospective, Randomized, Double-blind, Placebo-controlled Trial

Treatment of chronic pelvic pain syndrome (CPPS) is challenging for patients and physicians once conventional therapies fail.

We hypothesize that combined sono-electro-magnetic therapy can improve refractory CPPS in men. In addition, we postulate that combined sono-electro-magnetic therapy as well as placebo therapy has a significant effect on brain activity detectable by functional MRI.

Inclusion Criteria:

• CPSS III
• symptomatic >3 months
• NIH-CPSI total score =/>15
• NIH-CPSI pain =/>8

Exclusion Criteria:

• post void residual >100mL
• urinary tract infection
• urethral stricture
• prostate cancer
• age <18 years
• claustrophobia
• pacemaker, neurostimulator, insulin / pain pump