Effects of Single Oral Dose Dapagliflozin QT Study

A Double-blind, Randomized, Four-period Crossover Study to Assess the Effects of Single Oral Dose Dapagliflozin Administration on QTc Interval Compared to Placebo, Using AVELOX™ (Moxifloxacin) as a Positive Control, in Healthy Male Volunteers Age 18 to 45 Years

The main purpose of this study is to examine the effect of dapagliflozin on electronic measures of heart beats in healthy males

Inclusion Criteria:

• Healthy males age 18 to 45 years of age, who are not currently taking any medications
• Normal screening results including a physical examination, laboratory tests, heart rate, blood pressure, and ECG (electronic measure of the heart)

Exclusion Criteria:

• No personal or family history of significant heart problems
• No use of over the counter medications within 7 days of the study
• No use of prescription medicaiton within 1 month of the study