Safety and Feasibility Study of the Chartis System With Heterogeneous Emphysema Prior to Endobronchial Lung Volume Reduction (ELVR)

A Safety and Feasibility Study of the Chartis System in Subjects With Heterogeneous Emphysema Prior to Endobronchial Lung Volume Reduction (ELVR)

The purpose of this study is to evaluate the safety and feasibility of the Chartis System in measuring air flow and pressures in isolated lung compartments in emphysema patients prior to endobronchial lung volume reduction (ELVR).

Inclusion Criteria:

• Heterogeneous emphysema as determined by high-resolution CT scan
• Scheduled for clinically indicated ELVR procedure

Exclusion Criteria:

• Hyperexcretive chronic bronchitis or excessive sputum secretion
• Active pulmonary infection
• Active asthma or lung hyper-responsiveness