BMS-741672 for Diabetic Neuropathic Pain

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Crossover Trial to Evaluate the Efficacy and Safety of BMS-741672 in Patients With Diabetic Neuropathic Pain

The purpose of the study is to determine whether BMS-741672 improves neuropathic pain in diabetic patients.

Inclusion Criteria:

• Type 1 or 2 diabetics with painful, distal, symmetrical, sensory-motor neuropathy attributed to diabetes, of at least 12 months duration
• Screening HbA1c of ≥ 7% and ≤ 10%
• BMI ≤ 40 kg/m2

Exclusion Criteria:

• Patients with clinically significant, progressive, or potentially unstable disease of any body system including cardiovascular, gastrointestinal, central nervous system (CNS), psychiatric, endocrine (other than diabetes), tuberculosis or renal
• Women of childbearing potential