Patients (N=102) who meet diagnostic criteria for alcohol, cocaine, marijuana, or opiate abuse or dependence will meet with research staff on two days for quit preparation sessions (2 per day). These sessions include testing a breath sample for evidence of smoking twice each day (separated by at least 5 hours), counseling based on Public Health Service (PHS) guidelines for quitting smoking during the second session each day, and setting a quit date. After these sessions, participants will be randomly assigned to one of two 4-week conditions: (a) standard care or (b) standard care plus prize CM for smoking abstinence with the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Nicotine withdrawal and related measures will be assessed throughout the intervention. Follow-up data will be collected through 6-months post-quit date.

Inclusion Criteria:

• current alcohol, cocaine, marijuana, or opiate abuse or dependence
• smoke ≥ 10 cigarettes per day
• expired CO > 8 ppm
• self-reported interest in quitting smoking,
• ≥ 18 years old
• willing to provide names, addresses and phone numbers of individuals to assist in locating the participant for follow-up evaluations,
• English speaking

Exclusion Criteria:

• currently receiving behavioral therapy or pharmacotherapy for smoking plan to use pharmacotherapy in this quit attempt
• serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
• cognitive impairment
• in recovery for pathological gambling