Metoclopramide for Migraine: A Dose Finding Study

Metoclopramide for Acute Migraine: A Dose Finding Study

Metoclopramide is an effective intravenous treatment for acute migraine attacks, but we do not know the best dose to administer. This study compares three different doses of metoclorpamide.

Patients with acute migraine attacks are eligible for enrollment if they present to the emergency department of Montefiore Medical Center. Pain scores are assessed at baseline and every 30 minutes for two hours, and then again by telephone 48 hours after discharge

Inclusion Criteria:

• acute migraine

Exclusion Criteria:

• secondary cause of headache
• lumbar puncture
• allergy or intolerance to study medication