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| Name | Class |
|---|---|
| Oslo University Hospital | OTHER |
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Study hypothesis: Multifactorial risk reduction in coronary heart disease can reduce the risk of new coronary heart disease and death
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Multifactorial intervention | Active Comparator | Smoking cessation betablocker, diuretics, ACEI, ARB, statins, ezetimibe training influenza vaccine weight reduction metformin, glimepiride, insulin |
|
| Control | No Intervention | no intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| smoking cessation | Behavioral | NRT and varenicline |
| |
| Measure | Description | Time Frame |
|---|---|---|
| New cardiovascular events (MACE) | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Serena Tonstad, dr.med. | Ullevaal University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sorlandet Hospital | Arendal | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39323439 | Derived | Kaldal A, Tonstad S, Jortveit J. Self-reported smoking status and exhaled carbon monoxide in secondary preventive follow-up after coronary heart events: Do our patients tell the truth? Tob Prev Cessat. 2024 Sep 25;10. doi: 10.18332/tpc/191843. eCollection 2024. | |
| 37710178 | Derived | Kaldal A, Tonstad S, Jortveit J. Sex differences in secondary preventive follow-up after coronary heart events. BMC Cardiovasc Disord. 2023 Sep 14;23(1):459. doi: 10.1186/s12872-023-03483-6. |
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| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| D004232 | Diuretics |
| D000806 | Angiotensin-Converting Enzyme Inhibitors |
| D019161 | Hydroxymethylglutaryl-CoA Reductase Inhibitors |
| D000069438 | Ezetimibe |
| D007252 | Influenza Vaccines |
| D008687 | Metformin |
| C057619 | glimepiride |
| D007328 | Insulin |
| ID | Term |
|---|---|
| D045283 | Natriuretic Agents |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| betablocker, diuretics, ACEI, ARB, |
| Drug |
blood pressure control according to ESC guidelines |
|
| statins, ezetimibe | Drug | Cholesterol reduction according to ESC guidelines |
|
| training | Behavioral | daily walking |
|
| influenza vaccine | Biological | vaccine (FLuarix, Influvac etc) |
|
| metformin, glimepiride, insulin | Drug | s.glucose control according to ESC guidelines |
|
| weight reduction | Behavioral | diet tips |
|
| 37118703 | Derived | Kaldal A, Tonstad S, Jortveit J. Association of Troponin T measurements with long-term outcomes in patients with coronary artery disease participating in a secondary prevention trial. BMC Cardiovasc Disord. 2023 Apr 28;23(1):210. doi: 10.1186/s12872-023-03249-0. |
| 34915839 | Derived | Kaldal A, Tonstad S, Jortveit J. Long-term hospital-based secondary prevention of coronary artery disease: a randomized controlled trial. BMC Cardiovasc Disord. 2021 Dec 16;21(1):600. doi: 10.1186/s12872-021-02426-3. |
| D011480 | Protease Inhibitors |
| D004791 | Enzyme Inhibitors |
| D045504 | Molecular Mechanisms of Pharmacological Action |
| D000924 | Anticholesteremic Agents |
| D000960 | Hypolipidemic Agents |
| D000963 | Antimetabolites |
| D057847 | Lipid Regulating Agents |
| D045506 | Therapeutic Uses |
| D001384 | Azetidines |
| D001385 | Azetines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D014765 | Viral Vaccines |
| D014612 | Vaccines |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D001645 | Biguanides |
| D006146 | Guanidines |
| D000578 | Amidines |
| D009930 | Organic Chemicals |
| D011384 | Proinsulin |
| D061385 | Insulins |
| D010187 | Pancreatic Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |