Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest

Corticosteroids Therapy in Refractory Shock Following Cardiac Arrest

The major goal of this project is to determine whether the use of physiologic doses of corticosteroids will decrease time to shock reversal, alters the inflammatory cascade, and alters microcirculatory flow in post-cardiac arrest patients.

Inclusion Criteria:

• Greater than 18 years old
• Either pre-hospital cardiac arrest and ROSC or Inpatient Cardiac Arrest with resultant ROSC
• Vasopressor dependent for a minimum of 1 hour post-arrest

Exclusion Criteria:

• Pregnant
• Indication for Corticosteroids outside of current research proposal
• DNR or comfort care measures
• Presence of septic shock
• Chronic Use (>1week) of oral Corticosteroids in the last year