Treatment of Incomplete Abortion With 600 Mcg Oral Misoprostol Compared to Standard Surgical Treatment

Misoprostol for Treatment of Incomplete Abortion

This study aims to compare the efficacy, side effects profile and acceptability of a single dose of 600mcg misoprostol taken orally compared to standard surgical treatment as per local protocols for the treatment of incomplete abortion.

Inclusion Criteria:

• past or present history of vaginal bleeding during pregnancy
• open cervical os
• evidence of incomplete abortion with substantial debris in the uterus (if using ultrasound)
• surgical evacuation of the uterus would be advised as course of action if misoprostol was not available
• generally in good health
• woman lives or works within one hour of study site
• woman willing to provide contact information for follow up purposes
• informed consent given

Exclusion Criteria:

• contraindications to study drug
• uterine size larger than 12 weeks LMP
• signs of severe infection