Effect of Vitamin D Treatment in Primary Hyperparathyroidism

Effect of Vitamin D Treatment in Primary Hyperparathyroidism

The primary aim of the study is to assess whether 6-months of vitamin D supplements can decrease PTH compared with placebo treatment in primary hyperparathyroidism.

The study investigates effects and safety of six months of vitamin D supplementation before and after surgery in primary hyperparathyroidism. Effects are assessed as changes in calcium homeostasis, bone metabolism, quality of life, and muscle strength and function.

Inclusion Criteria:

• P-Ca-ion > 1,30 mmol/l
• P-PTH > 5 pmol/l
• P-OH25-vitamin D < 80 nmol/l

Exclusion Criteria:

• P-creatinin > 120 mumol/l
• usage of Etalpha, Mimpara
• Cancer
• Sarcoidosis
• malabsorption
• pancreatitis
• alcohol abuse
• pregnancy