The purpose of this trial is to study the effect of adjuvant or immediate hormonal therapy, versus placebo, in subjects who have either undergone a primary therapy (principally radical prostatectomy or radiotherapy) or who were otherwise to be managed by watchful waiting.

Inclusion Criteria:

• Clinical diagnosis of non-metastatic cancer of the prostate gland
• Patient to be 18 years and above

Exclusion Criteria:

• Previous systemic therapy for prostate cancer
• Previous history of another form of cancer (not prostate) within 5 years of study start.