Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus

A Phase II, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety and Efficacy of Ipamorelin Compared to Placebo for the Management of Post-Operative Ileus in Patients

The purpose of this study is to determine if ipamorelin is safe and effective in the management of post-operative ileus.

The safety and efficacy of ipamorelin in the management of post-operative ileus

Inclusion Criteria:

• willing to comply with protocol
• undergoing bowel resection surgery
• ASA Class I-III
• Females must not be pregnant
• Body weight 40-150 kg

Exclusion Criteria:

• mentally incompetent or unable to provide informed consent
• clinically unstable
• significant liver disease
• clinically significant lab or EKG abnormalities
• alcohol or illicit drug abuse
• history of or current surgery that would prevent proper evaluation of safety or efficacy of drug