Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis

Fase IV Clinical Trial to Evaluate Chondroitin Sulphate Efficacy and Safety in Patients With Knee Osteoarthritis and Psoriasis

The purpouse of this study is to determine the efficacy and safety of chondroitin sulphate conventional treatment in patients with both knee osteoarthritis and plaque psoriasis.

Inclusion Criteria:

• Primary knee OA according to ACR criteria;
• OA of radiological stages 1 to 3 according to Kellgren-Lawrence;
• VAS of pain ≥30;
• PASI ≥ 5.

Exclusion Criteria:

• Known allergy to chondroitin sulphate;
• Other bone and articular diseases such as chondrocalcinosis, Paget's disease, rheumatoid arthritis, psoriatic arthritis, acromegaly, hemochromatosis, Wilson's disease;
• Patients with skin conditions that could interfere in the clinical trial evaluation