Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation

Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation

The Study aims to prospectively survey the incidence of respiratory virus infections using molecular methodologies, in children undergoing hematopoietic stem cell transplantation

Samples will be collected with a nasopharyngeal wash and processed for direct fluorescent antibody, culture and Polymerase chain reaction (PCR)

Inclusion Criteria:

• Age: Birth to 18 years.
• Patients undergoing an allogeneic HSCT for any disease.
• Parent or guardian willing to sign informed consent.

Exclusion Criteria:

• Intra nasal lesion which precludes the performance of the nasopharyngeal wash.
• Patients on Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP).