Efficacy of Cantharidin in Molluscum Contagiosum

Efficacy of Cantharidin in Molluscum Contagiosum: A Randomized, Blinded, Placebo-Controlled Prospective Study

The University of North Carolina Department of Dermatology is conducting a clinical trial to evaluate a drug called cantharidin in the treatment of molluscum contagiosum. Molluscum is a common dermatologic disorder caused by a poxvirus. Molluscum typically presents with many flesh-colored bumps on the skin. It goes away on its own, though can last several months to several years. Cantharidin is a topical medicine which is applied at the clinic visit. It is well tolerated by the majority of children.

Inclusion Criteria:

• Anyone aged 5-10 years with the clinical diagnosis of molluscum contagiosum.

Exclusion Criteria:

• Anyone with immunosuppression including HIV or previous organ transplantation.
• Anyone taking immunosuppressive medications.
• Anyone who has previously received treatment with cantharidin.
• Any female who has had her first menstrual period.