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| ID | Type | Description | Link |
|---|---|---|---|
| GERCOR-OLD | |||
| EudraCT-2007004103-36 |
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RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.
PURPOSE: This clinical trial is studying how well combination chemotherapy works in treating older patients with solid tumour.
OBJECTIVES:
Primary
Secondary
OUTLINE: This is a multicenter study. Patients receive one of the following regimens according to cancer diagnosis and principal investigator preference. All regimens last 3 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chemotherapy | Other | chemotherapy regimen |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| chemotherapy | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| chemotherapy feasibility | ability to deliver at least 3 months of the planned regimen therapy. | from inclusion to 3 months |
| Number of patients receiving therapeutic dose-intensive therapy (doses must be at least equivalent to two-thirds the dose that is usually administered according to AMM recommendations) | dose reduction < 33% | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Grade 3-4 toxicities according to NCI-CTCAE version 3 | from inclusion to 3 months |
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DISEASE CHARACTERISTICS:
PATIENT CHARACTERISTICS:
PRIOR CONCURRENT THERAPY:
Chemonaive patient.
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| Name | Affiliation | Role |
|---|---|---|
| Elisabeth Carola, MD | C.H. Senlis | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Radiotherapie Oncologie Moyenne Garonne | Agen | 47000 | France | |||
| Centre Hospitalier de Castelluccio |
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| Ajaccio |
| 20176 |
| France |
| Centre Hospitalier d'Ardeche Meridionale | Aubenas | 07205 | France |
| Centre Hospitalier d'Auxerre | Auxerre | 89011 | France |
| Institut Sainte Catherine | Avignon | 84000 | France |
| Hopital Duffaut | Avignon | 84902 | France |
| Centre Hospitalier de Beauvais | Beauvais | 60021 | France |
| Clinique des Cedres | Cornebarrieu | 31700 | France |
| Centre Medico-Chirurgical et Obstetrique d'Evry | Évry | 91000 | France |
| Hopital Clarac | Fort de France Cedex | 97261 | France |
| Centre Hospitalier Intercommunal des Alpes du Sud | Gap | 05007 | France |
| Centre Hospitalier de Lagny | Lagny-sur-Marne | 77405 | France |
| Centre Hospitalier St. Joseph St. Luc | Lyon | 69007 | France |
| Hopital Prive Jean Mermoz | Lyon | 69008 | France |
| Centre Hospitalier Chanaux | Mâcon | 71018 | France |
| Centre Hospitalier de Montelimar | Montélimar | 26200 | France |
| Hopital Bichat - Claude Bernard | Paris | 75018 | France |
| Hopital de la Croix St. Simon | Paris | 75020 | France |
| Hopital Saint Antoine | Paris | 75571 | France |
| Hopital Tenon | Paris | 75970 | France |
| Hopital Rene Dubos | Pontoise | 95300 | France |
| Institut Jean Godinot | Reims | 51056 | France |
| Centre Hospitalier Prive Saint-Gregoire | Saint-Grégoire | 35768 | France |
| Centre Hospitalier de Saint-Quentin | Saint-Quentin | 02321 | France |
| Centre Hospitalier de Semur en Auxois | Semur-en-Auxois | 21140 | France |
| C.H. Senlis | Senlis | 60309 | France |
| Hopital Foch | Suresnes | 92151 | France |
| Centre hospitalier de Tonnerre | Tonnerre | 89700 | France |
| Centre Hospitalier Villeneuve Saint Georges | Villeneuve-Saint-Georges | 94195 | France |
| ID | Term |
|---|---|
| D004358 | Drug Therapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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