slow enrollment , interim analysis conducted.

The purpose of this study is to determine the safety and efficacy of Vitreosolve in diabetic retinopathy patients.

Inclusion Criteria:

• Subjects with a history of systemic diabetes (type I or II)
• Subject with a documented history of Non Proliferative Diabetic Retinopathy (NPDR)
• Subjects with no PVD at baseline exam in the study eye.

Exclusion Criteria:

• Subjects with Retinal pathology in the study eye other than (NPDR)
• Subjects with high myopia in the study eye
• Subjects who have monocular vision or contra lateral vision of 20/200 or worse BCVA in the non-study eye.
• Subjects with an aphakic study eye or if pseudophakic, cataract extraction surgery less than 6 months prior to study enrollment
• Subjects that have had either vitrectomy surgery, intravitreal injections, or laser treatments in the study eye.