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| ID | Type | Description | Link |
|---|---|---|---|
| cyanoacrylate1 |
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| Name | Class |
|---|---|
| North Karelia Central Hospital | OTHER |
| Paijat-Hame Hospital District | OTHER |
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The purpose of the study is to investigate whether chronic postoperative pain is less frequent and quality of life better when inguinal mesh is fixed by using tissue glue compared to conventional sutures in inguinal hernioplasty.
Repair of inguinal hernia in one of the most frequently performed surgical operation in western world. The technique of choice is currently to support inguinal tissues by using polypropylene mesh. Chronic postoperative pain and discomfort occur in 25-30% of patients after inguinal hernioplasty. Pain might be related to mesh fixation by sutures. This randomized study investigates whether mesh fixation by tissue glue (cyanoacrylate) is better than sutures. The patients are followed 1 year postoperatively. Pain, quality of life, operative parameters (time, cost) and recurrences are reported.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | No Intervention | mesh fixation by absorbable sutures | |
| 2 | Experimental | mesh fixation by cyanoacrylate glue |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cyanoacrylate glue | Procedure | 1 ml glue |
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| Measure | Description | Time Frame |
|---|---|---|
| postoperative pain | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| hernia recurrence, quality of life | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pekka Miettinen, MD, PhD | University hospital of Kuopio, Finland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hannu Paajanen | Kuopio | Kuopio | 1777 | Finland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12415411 | Background | Ong CC, Jacobsen AS, Joseph VT. Comparing wound closure using tissue glue versus subcuticular suture for pediatric surgical incisions: a prospective, randomised trial. Pediatr Surg Int. 2002 Sep;18(5-6):553-5. doi: 10.1007/s00383-002-0728-0. Epub 2002 Jun 14. | |
| 27864616 | Derived | Matikainen M, Kossi J, Silvasti S, Hulmi T, Paajanen H. Randomized Clinical Trial Comparing Cyanoacrylate Glue Versus Suture Fixation in Lichtenstein Hernia Repair: 7-Year Outcome Analysis. World J Surg. 2017 Jan;41(1):108-113. doi: 10.1007/s00268-016-3801-x. |
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| ID | Term |
|---|---|
| D006552 | Hernia, Inguinal |
| ID | Term |
|---|---|
| D046449 | Hernia, Abdominal |
| D006547 | Hernia |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| C040229 | MK 6 cyanoacrylate |
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| 21710480 | Derived | Paajanen H, Kossi J, Silvasti S, Hulmi T, Hakala T. Randomized clinical trial of tissue glue versus absorbable sutures for mesh fixation in local anaesthetic Lichtenstein hernia repair. Br J Surg. 2011 Sep;98(9):1245-51. doi: 10.1002/bjs.7598. Epub 2011 Jun 28. |